Certified Polysomnographic Technician (CPSGT) 2025 – 400 Free Practice Questions to Pass the Exam

Secondary periodic limb movement disorder (PLMD) can be associated with various underlying conditions, and blood iron deficiency is identified as one of the potential causes. Iron plays a critical role in the functioning of neurotransmitters involved in regulating movement, including dopamine. Low iron levels may result in altered dopamine metabolism, which can lead to the development of PLMS. This condition often manifests in people with iron-deficiency anemia, making it a significant factor to consider when evaluating the causes of secondary PLMS.

While vitamin B12 deficiency, sleep deprivation, and caffeine sensitivity can contribute to sleep disturbances and other neurological issues, their direct association with secondary PLMS is less established compared to blood iron deficiency. Understanding the link between iron levels and periodic limb movements is crucial for diagnosing and managing conditions that lead to secondary PLMS effectively.